Allergic reactivity and IgG subclasses to a proteinase fraction of Setaria digitata in filariasis.
Identifieur interne : 00C321 ( Main/Exploration ); précédent : 00C320; suivant : 00C322Allergic reactivity and IgG subclasses to a proteinase fraction of Setaria digitata in filariasis.
Auteurs : M K Beuria [Inde] ; M. Bal ; M K DasSource :
- Journal of helminthology [ 0022-149X ] ; 1995.
Descripteurs français
- KwdFr :
- Animaux, Anticorps antihelminthe (sang), Antigènes d'helminthe (immunologie), Antigènes d'helminthe (métabolisme), Bovins, Concentration en ions d'hydrogène, Cysteine endopeptidases (immunologie), Cysteine endopeptidases (métabolisme), Filariose lymphatique (immunologie), Humains, Hypersensibilité immédiate, Immunoglobuline G (sang), Inde, Infection à Setaria (immunologie), Inhibiteurs de la cystéine protéinase, Porteur sain, Setaria (nématode) (enzymologie), Setaria (nématode) (immunologie), Tests intradermiques, Zinc (physiologie).
- MESH :
- enzymologie : Setaria (nématode).
- immunologie : Antigènes d'helminthe, Cysteine endopeptidases, Filariose lymphatique, Infection à Setaria, Setaria (nématode).
- métabolisme : Antigènes d'helminthe, Cysteine endopeptidases.
- physiologie : Zinc.
- sang : Anticorps antihelminthe, Immunoglobuline G.
- Animaux, Bovins, Concentration en ions d'hydrogène, Humains, Hypersensibilité immédiate, Inde, Inhibiteurs de la cystéine protéinase, Porteur sain, Tests intradermiques.
- Wicri :
- geographic : Inde.
English descriptors
- KwdEn :
- Animals, Antibodies, Helminth (blood), Antigens, Helminth (immunology), Antigens, Helminth (metabolism), Carrier State, Cattle, Cysteine Endopeptidases (immunology), Cysteine Endopeptidases (metabolism), Cysteine Proteinase Inhibitors, Elephantiasis, Filarial (immunology), Humans, Hydrogen-Ion Concentration, Hypersensitivity, Immediate, Immunoglobulin G (blood), India, Intradermal Tests, Setaria Nematode (enzymology), Setaria Nematode (immunology), Setariasis (immunology), Zinc (physiology).
- MESH :
- chemical , blood : Antibodies, Helminth, Immunoglobulin G.
- chemical , immunology : Antigens, Helminth, Cysteine Endopeptidases.
- chemical , metabolism : Antigens, Helminth, Cysteine Endopeptidases.
- chemical , physiology : Zinc.
- geographic : India.
- enzymology : Setaria Nematode.
- immunology : Elephantiasis, Filarial, Setaria Nematode, Setariasis.
- Animals, Carrier State, Cattle, Cysteine Proteinase Inhibitors, Humans, Hydrogen-Ion Concentration, Hypersensitivity, Immediate, Intradermal Tests.
Abstract
A low molecular weight fraction (30 KDa) of the cattle filarial parasite Setaria digitata that was earlier demonstrated to have allergenic activity was characterized to be a zinc-dependent cysteine proteinase. Immediate type hypersensitivity (ITH) reaction to the proteinase was evaluated in lymphatic filariasis patients and in endemic controls from Orissa, India. The extent of ITH positivity to the proteinase in infected individuals ranged from 20% in chronic filariasis (CP) patients group to 56% in asymptomatic microfilaraemic carriers (AS). About 62% of endemic normals (EN) were also ITH positive. The serum levels of IgG subclasses were compared in ITH positive and ITH negative filarial patients (AS and CP) as well as in endemic normals (EN) respectively. IgG4 levels were found to be inversely dependent on ITH reaction only in AS groups. Asymptomatic patients (AS) with positive ITH reactivity had lower IgG4 than ITH negative individuals from the same group. The serum levels of other IgG subclasses except IgG2, did not correlate with ITH reactivity. IgG2 levels were higher in ITH negative EN and CP patients but not in the AS group.
PubMed: 8522762
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 005337
- to stream PubMed, to step Curation: 005337
- to stream PubMed, to step Checkpoint: 005337
- to stream Ncbi, to step Merge: 00B643
- to stream Ncbi, to step Curation: 00B643
- to stream Ncbi, to step Checkpoint: 00B643
- to stream Main, to step Merge: 00CC36
- to stream Main, to step Curation: 00C321
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Allergic reactivity and IgG subclasses to a proteinase fraction of Setaria digitata in filariasis.</title><author><name sortKey="Beuria, M K" sort="Beuria, M K" uniqKey="Beuria M" first="M K" last="Beuria">M K Beuria</name><affiliation wicri:level="1"><nlm:affiliation>Parasite Immunology Division, Regional Medical Centre (ICMR), Bhubaneswar, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Parasite Immunology Division, Regional Medical Centre (ICMR), Bhubaneswar</wicri:regionArea><wicri:noRegion>Bhubaneswar</wicri:noRegion></affiliation></author><author><name sortKey="Bal, M" sort="Bal, M" uniqKey="Bal M" first="M" last="Bal">M. Bal</name></author><author><name sortKey="Das, M K" sort="Das, M K" uniqKey="Das M" first="M K" last="Das">M K Das</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1995">1995</date><idno type="RBID">pubmed:8522762</idno><idno type="pmid">8522762</idno><idno type="wicri:Area/PubMed/Corpus">005337</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">005337</idno><idno type="wicri:Area/PubMed/Curation">005337</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">005337</idno><idno type="wicri:Area/PubMed/Checkpoint">005337</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">005337</idno><idno type="wicri:Area/Ncbi/Merge">00B643</idno><idno type="wicri:Area/Ncbi/Curation">00B643</idno><idno type="wicri:Area/Ncbi/Checkpoint">00B643</idno><idno type="wicri:doubleKey">0022-149X:1995:Beuria M:allergic:reactivity:and</idno><idno type="wicri:Area/Main/Merge">00CC36</idno><idno type="wicri:Area/Main/Curation">00C321</idno><idno type="wicri:Area/Main/Exploration">00C321</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Allergic reactivity and IgG subclasses to a proteinase fraction of Setaria digitata in filariasis.</title><author><name sortKey="Beuria, M K" sort="Beuria, M K" uniqKey="Beuria M" first="M K" last="Beuria">M K Beuria</name><affiliation wicri:level="1"><nlm:affiliation>Parasite Immunology Division, Regional Medical Centre (ICMR), Bhubaneswar, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Parasite Immunology Division, Regional Medical Centre (ICMR), Bhubaneswar</wicri:regionArea><wicri:noRegion>Bhubaneswar</wicri:noRegion></affiliation></author><author><name sortKey="Bal, M" sort="Bal, M" uniqKey="Bal M" first="M" last="Bal">M. Bal</name></author><author><name sortKey="Das, M K" sort="Das, M K" uniqKey="Das M" first="M K" last="Das">M K Das</name></author></analytic><series><title level="j">Journal of helminthology</title><idno type="ISSN">0022-149X</idno><imprint><date when="1995" type="published">1995</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Antibodies, Helminth (blood)</term><term>Antigens, Helminth (immunology)</term><term>Antigens, Helminth (metabolism)</term><term>Carrier State</term><term>Cattle</term><term>Cysteine Endopeptidases (immunology)</term><term>Cysteine Endopeptidases (metabolism)</term><term>Cysteine Proteinase Inhibitors</term><term>Elephantiasis, Filarial (immunology)</term><term>Humans</term><term>Hydrogen-Ion Concentration</term><term>Hypersensitivity, Immediate</term><term>Immunoglobulin G (blood)</term><term>India</term><term>Intradermal Tests</term><term>Setaria Nematode (enzymology)</term><term>Setaria Nematode (immunology)</term><term>Setariasis (immunology)</term><term>Zinc (physiology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Anticorps antihelminthe (sang)</term><term>Antigènes d'helminthe (immunologie)</term><term>Antigènes d'helminthe (métabolisme)</term><term>Bovins</term><term>Concentration en ions d'hydrogène</term><term>Cysteine endopeptidases (immunologie)</term><term>Cysteine endopeptidases (métabolisme)</term><term>Filariose lymphatique (immunologie)</term><term>Humains</term><term>Hypersensibilité immédiate</term><term>Immunoglobuline G (sang)</term><term>Inde</term><term>Infection à Setaria (immunologie)</term><term>Inhibiteurs de la cystéine protéinase</term><term>Porteur sain</term><term>Setaria (nématode) (enzymologie)</term><term>Setaria (nématode) (immunologie)</term><term>Tests intradermiques</term><term>Zinc (physiologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Antibodies, Helminth</term><term>Immunoglobulin G</term></keywords><keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>Antigens, Helminth</term><term>Cysteine Endopeptidases</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Antigens, Helminth</term><term>Cysteine Endopeptidases</term></keywords><keywords scheme="MESH" type="chemical" qualifier="physiology" xml:lang="en"><term>Zinc</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>India</term></keywords><keywords scheme="MESH" qualifier="enzymologie" xml:lang="fr"><term>Setaria (nématode)</term></keywords><keywords scheme="MESH" qualifier="enzymology" xml:lang="en"><term>Setaria Nematode</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Antigènes d'helminthe</term><term>Cysteine endopeptidases</term><term>Filariose lymphatique</term><term>Infection à Setaria</term><term>Setaria (nématode)</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Elephantiasis, Filarial</term><term>Setaria Nematode</term><term>Setariasis</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Antigènes d'helminthe</term><term>Cysteine endopeptidases</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Zinc</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Anticorps antihelminthe</term><term>Immunoglobuline G</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Carrier State</term><term>Cattle</term><term>Cysteine Proteinase Inhibitors</term><term>Humans</term><term>Hydrogen-Ion Concentration</term><term>Hypersensitivity, Immediate</term><term>Intradermal Tests</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Bovins</term><term>Concentration en ions d'hydrogène</term><term>Humains</term><term>Hypersensibilité immédiate</term><term>Inde</term><term>Inhibiteurs de la cystéine protéinase</term><term>Porteur sain</term><term>Tests intradermiques</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Inde</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A low molecular weight fraction (30 KDa) of the cattle filarial parasite Setaria digitata that was earlier demonstrated to have allergenic activity was characterized to be a zinc-dependent cysteine proteinase. Immediate type hypersensitivity (ITH) reaction to the proteinase was evaluated in lymphatic filariasis patients and in endemic controls from Orissa, India. The extent of ITH positivity to the proteinase in infected individuals ranged from 20% in chronic filariasis (CP) patients group to 56% in asymptomatic microfilaraemic carriers (AS). About 62% of endemic normals (EN) were also ITH positive. The serum levels of IgG subclasses were compared in ITH positive and ITH negative filarial patients (AS and CP) as well as in endemic normals (EN) respectively. IgG4 levels were found to be inversely dependent on ITH reaction only in AS groups. Asymptomatic patients (AS) with positive ITH reactivity had lower IgG4 than ITH negative individuals from the same group. The serum levels of other IgG subclasses except IgG2, did not correlate with ITH reactivity. IgG2 levels were higher in ITH negative EN and CP patients but not in the AS group.</div></front></TEI><affiliations><list><country><li>Inde</li></country></list><tree><noCountry><name sortKey="Bal, M" sort="Bal, M" uniqKey="Bal M" first="M" last="Bal">M. Bal</name><name sortKey="Das, M K" sort="Das, M K" uniqKey="Das M" first="M K" last="Das">M K Das</name></noCountry><country name="Inde"><noRegion><name sortKey="Beuria, M K" sort="Beuria, M K" uniqKey="Beuria M" first="M K" last="Beuria">M K Beuria</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 00C321 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 00C321 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:8522762
|texte= Allergic reactivity and IgG subclasses to a proteinase fraction of Setaria digitata in filariasis.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:8522762" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a LymphedemaV1
| This area was generated with Dilib version V0.6.31. |  |